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  • 產(chǎn)品名稱:兔抗MBP多克隆抗體

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中文名稱:  兔抗MBP多克隆抗體  

英文名稱: Anti-MBP rabbit polyclonal antibody

別      名: MGC99675

相關(guān)類別: 一抗

儲(chǔ)      存: 冷凍(-20℃) 避光

宿      主: Rabbit

抗      原: MBP

反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Applications:

WB

Name of antibody:

MBP

Immunogen:

Synthetic peptide of human MBP

Full name:

myelin basic protein

Synonyms:

MGC99675

SwissProt:

P02686

WB Predicted band size:

33 kDa

WB Positive control:

Rat brain, Mouse brain and Rat hippocampus Tissue

WB Recommended dilution:

500-1000


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