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  • 產(chǎn)品名稱：兔抗MAPK14多克隆抗體

  • 產(chǎn)品型號：100ul
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：1560
  • 產(chǎn)品庫存：60
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詳情介紹：

中文名稱：  兔抗MAPK14多克隆抗體 

英文名稱： Anti-MAPK14 rabbit polyclonal antibody

別      名： mitogen-activated protein kinase 14; RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA


相關(guān)類別： 一抗

儲      存： 冷凍（-20℃）

宿      主： Rabbit

抗      原： MAPK14

反應(yīng)種屬： Human, Mouse, Rat

標(biāo) 記 物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Applications:

ELISA, IHC

Name of antibody:

MAPK14

Immunogen:

Fusion protein of human MAPK14

Full name:

mitogen-activated protein kinase 14

Synonyms:

RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA

SwissProt:

Q16539

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

100-300



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