英文名稱: SF3A3 Antigen (Recombinant Protein)
別 名: splicing factor 3a subunit 3; PRP9; PRPF9; SAP61; SF3a60
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述
Full name: |
splicing factor 3a subunit 3 |
Synonyms: |
PRP9; PRPF9; SAP61; SF3a60 |
Swissprot: |
Q12874 |
Gene Accession: |
BC002395 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. |