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  • 產(chǎn)品名稱：RFFL 抗原（重組蛋白）

  • 產(chǎn)品型號：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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RFFL 抗原（重組蛋白）為感謝各大科研機(jī)構(gòu)長期以來對我發(fā)貨單的支持，我司特在精品發(fā)布的同時(shí)開展一周促銷活動，主要形式為送禮活動，低至9折起售，凡買及送的哦！好機(jī)會不錯(cuò)過！了解詳細(xì)信息來電咨詢哦！也可以通過在本站留言的，我們一定在半個(gè)工作內(nèi)給您回復(fù)。
詳情介紹：
中文名稱： RFFL 抗原（重組蛋白）

英文名稱： RFFL Antigen (Recombinant Protein)

別     名：  ring finger and FYVE-like domain containing E3 ubiquitin protein ligase; CARP2; FRING; CARP-2; RNF189; RNF34L; RIFIFYLIN

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 97-316 amino acids of human RFFL

技術(shù)規(guī)格

Full name:

ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

Synonyms:

CARP2; FRING; CARP-2; RNF189; RNF34L; RIFIFYLIN

Swissprot:

Q8WZ73

Gene Accession:

BC028424

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Mediates 'Lys-48'-linked polyubiquitination of PRR5L and its subsequent proteasomal degradation thereby indirectly regulating cell migration through the mTORC2 complex. Also ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate apoptosis downstream of death domain receptors. Also negatively regulates the tumor necrosis factor-mediated signaling pathway through targeting of RIPK1 to ubiquitin-mediated proteasomal degradation.





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