英文名稱:CD247 Antigen (Recombinant Protein)
別 名: CD247 molecule; T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
儲 存: 冷凍(-20℃)
相關(guān)類別:抗原
Full name: |
CD247 molecule |
Synonyms: |
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA |
Swissprot: |
P20963 |
Gene Accession: |
BC025703 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |