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  • 產(chǎn)品名稱：C7 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：


中文名稱： C7 抗原（重組蛋白）

英文名稱： C7 Antigen (Recombinant Protein)

別     名： complement component 7

儲     存： 冷凍（-20℃）  

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 644-843 amino acids of human C7


技術(shù)規(guī)格

Full name:

complement component 7

Swissprot:

P10643

Gene Accession:

BC063851

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The complement cascade is a multi-protein system that functions to clear pathogens from an infected host. Part of the innate (unchanging) immune system, the complement cascade consists of proteins and inactive zymogens that are present in blood and are stimulated by one of several triggers. Once stimulated, the cascade relays amplified responses throughout the body, ultimately activating the cell-killing membrane attack complex which can insert itself into the cell membrane and cause the cell to lyse. C7 (complement component 7) is an 843 amino acid secreted protein that participates in the formation of membrane attack complex (MAC), a complex that forms pores in the plasma membrane of target cells for innate and adaptive immune responses. As a membrane anchor, C7 exists as a monomer or dimer and can form multimeric rosettes with C5β. C7 defects are the cause of component C7 deficiency (C7D), characterized by recurrent bacterial infections caused by Neisseria meningitidis.





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