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  • 產(chǎn)品名稱：MRE11 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：800
  • 產(chǎn)品庫存：35
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中文名稱： MRE11 抗原（重組蛋白）

英文名稱： MRE11 Antigen (Recombinant Protein)

別     名：  MRE11 homolog, double strand break repair nuclease; ATLD; HNGS1; MRE11A; MRE11B

儲(chǔ)     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概    述

Fusion protein corresponding to N terminal 180 amino acids of human MRE11

技術(shù)規(guī)格

Full name:

MRE11 homolog, double strand break repair nuclease

Synonyms:

ATLD; HNGS1; MRE11A; MRE11B

Swissprot:

P49959

Gene Accession:

NP_005582

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.





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