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  • 產(chǎn)品名稱:兔抗MCM6多克隆抗體

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中文名稱:  兔抗MCM6多克隆抗體   

英文名稱: Anti-MCM6 rabbit polyclonal antibody

別      名: Mis5; P105MCM; MCG40308

抗      原: MCM6

儲      存: 冷凍(-20℃)

宿       主: Rabbit

相關(guān)類別: 一抗

反應(yīng)種屬: Human, Mouse, Rat

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Applications:

ELISA, WB, IHC

Name of antibody:

MCM6

Immunogen:

Fusion protein of human MCM6

Full name:

minichromosome maintenance complex component 6

Synonyms:

Mis5; P105MCM; MCG40308

SwissProt:

Q14566

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human cervical cancer and human tonsil

IHC Recommend dilution:

50-200

WB Predicted band size:

93 kDa

WB Positive control:

293T, K562, NIH/3T3 and hela cells

WB Recommended dilution:

500-2000





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