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  • 產品名稱：SEPTIN2 抗原（重組蛋白）

  • 產品型號：100ug
  • 產品廠商：通蔚生物
  • 產品價格：800
  • 產品庫存：35
  • 產品文檔：
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簡單介紹：
SEPTIN2 抗原（重組蛋白）一路走來依靠豐富的經(jīng)驗、優(yōu)良的抗體品質、充足的庫存、準確的交貨時間、具競爭力的價格優(yōu)勢等成為試劑盒行業(yè)的遙遙優(yōu)越者，當然這些都離不開大家的支持，讓客戶滿意，才是我們永恒的追求！
詳情介紹：

中文名稱： SEPTIN2 抗原（重組蛋白）

英文名稱： SEPTIN2 Antigen (Recombinant Protein)

別     名：  septin 2; DIFF6; NEDD5; SEPT2; NEDD-5; Pnutl3; hNedd5

儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1-371 amino acids of human SEPTIN2

技術規(guī)格

Full name:

septin 2

Synonyms:

DIFF6; NEDD5; SEPT2; NEDD-5; Pnutl3; hNedd5

Swissprot:

Q15019

Gene Accession:

BC033559

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.





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